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1

Opioid receptors: drivers to addiction?

Darcq, Emmanuel, Kieffer, Brigitte Lina

Journal:

Nature Reviews Neuroscience

Year:

2018

Language:

english

File:

PDF, 2.22 MB

english, 2018

2

Current strategies toward safer mu opioid receptor drugs for pain management

Ehrlich, Aliza T., Kieffer, Brigitte L., Darcq, Emmanuel

Journal:

Expert Opinion on Therapeutic Targets

Year:

2019

Language:

english

File:

PDF, 1.29 MB

english, 2019

3

Mechanisms for the Regulation of State Changes in the Central Nervous System : An Introduction

Donald W. Pfaff, Brigitte L. Kieffer, Larry W. Swanson

Journal:

Annals of the New York Academy of Sciences

Year:

2008

Language:

english

File:

PDF, 233 KB

english, 2008

4

Opioid receptors: From binding sites to visible molecules in vivo

Brigitte L. Kieffer, Christopher J. Evans

Journal:

Neuropharmacology

Year:

2009

Language:

english

File:

PDF, 603 KB

english, 2009

5

Opioids: first lessons from knockout mice

Brigitte L. Kieffer

Journal:

Trends in Pharmacological Sciences

Year:

1999

Language:

english

File:

PDF, 190 KB

english, 1999

6

Recent Findings on the Mechanism of Action of Morphine

Dr Olga Valverde,Rafael Maldonado,Brigitte L. Kieffer

Journal:

Year:

1998

Language:

english

File:

PDF, 315 KB

english, 1998

7

理想的な鎮痛薬を計算科学で設計

Kieffer, Brigitte L.

Journal:

Year:

2016

File:

PDF, 1.07 MB

2016

8

The Control of Reward Seeking

Darcq, Emmanuel, Kieffer, Brigitte L.

Journal:

Biological Psychiatry

Year:

2018

Language:

english

File:

PDF, 186 KB

english, 2018

9

Knock-in mice reveal nonsense-mediated mRNA decay in the brain

Candice Contet, Andrée Dierich, Brigitte L Kieffer

Journal:

Year:

2007

Language:

english

File:

PDF, 261 KB

english, 2007

10

Endogenous nociceptin/orphanin-fq in the dorsal hippocampus facilitates despair-related behavior

Celia Goeldner, David Reiss, Brigitte L. Kieffer, Abdel-Mouttalib Ouagazzal

Journal:

Year:

2010

Language:

english

File:

PDF, 453 KB

english, 2010

11

Mu-opioid receptors are not necessary for nortriptyline treatment of neuropathic allodynia

Yohann Bohren, Dzenan Karavelic, Luc-Henri Tessier, Ipek Yalcin, Claire Gavériaux-Ruff, Brigitte L. Kieffer, Marie-José Freund-Mercier, Michel Barrot

Journal:

European Journal of Pain

Year:

2010

Language:

english

File:

PDF, 345 KB

english, 2010

12

Respiratory function in adult mice lacking the µ-opioid receptor: role of δ-receptors

Marie-Pierre Morin-Surun, Eliane Boudinot, Christelle Dubois, Hans W. Matthes, Brigitte L. Kieffer, Monique Denavit-Saubié, Jean Champagnat, Arthur S. Foutz

Journal:

European Journal of Neuroscience

Year:

2001

Language:

english

File:

PDF, 424 KB

english, 2001

13

Melanocortin receptors and δ-opioid receptor mediate opposite signalling actions of POMC-derived peptides in CATH.a cells

Frédérique René, André Muller, Emmanuel Jover, Brigitte Kieffer, Bernard Koch, Jean-Philippe Loeffler

Journal:

European Journal of Neuroscience

Year:

1998

Language:

english

File:

PDF, 714 KB

english, 1998

14

Cannabinoid withdrawal syndrome is reduced in double mu and delta opioid receptor knockout mice

Anna Castañé, Patricia Robledo, Audrey Matifas, Brigitte L. Kieffer, Rafael Maldonado

Journal:

European Journal of Neuroscience

Year:

2003

Language:

english

File:

PDF, 163 KB

english, 2003

15

Acute antinociceptive responses in single and combinatorial opioid receptor knockout mice: distinct mu, delta and kappa tones

Miquel Martin, Audrey Matifas, Rafael Maldonado, Brigitte L. Kieffer

Journal:

European Journal of Neuroscience

Year:

2003

Language:

english

File:

PDF, 186 KB

english, 2003

16

Basal and morphine-evoked dopaminergic neurotransmission in the nucleus accumbens of MOR- and DOR-knockout mice

Vladimir I. Chefer, Brigitte L. Kieffer, Toni S. Shippenberg

Journal:

European Journal of Neuroscience

Year:

2003

Language:

english

File:

PDF, 295 KB

english, 2003

17

Cannabinoid receptor and WIN 55 212-2-stimulated [35S]-GTPγS binding in the brain of mu-, delta- and kappa-opioid receptor knockout mice

Fernando Berrendero, Victoria Mendizábal, Patricia Murtra, Brigitte L. Kieffer, Rafael Maldonado

Journal:

European Journal of Neuroscience

Year:

2003

Language:

english

File:

PDF, 155 KB

english, 2003

18

Agonists activate Gi1α or Gi2α fused to the human mu opioid receptor differently

Dominique Massotte, Karl Brillet, Brigitte Kieffer, Graeme Milligan

Journal:

Journal of Neurochemistry

Year:

2002

Language:

english

File:

PDF, 298 KB

english, 2002

19

Enhanced spontaneous activity of the mu opioid receptor by cysteine mutations: characterization of a tool for inverse agonist screening.

Karl Brillet, Brigitte L Kieffer, Dominique Massotte

Journal:

BMC Pharmacology

Year:

2003

Language:

english

File:

PDF, 1.89 MB

english, 2003

20

Lack of genotype effect on D1, D2 receptors and dopamine transporter binding in triple MOP-, DOP-, and KOP-opioid receptor knockout mice of three different genetic backgrounds

Ji-hoon Yoo, Alexis Bailey, Micheal Ansonoff, John E. Pintar, Audrey Matifas, Brigitte L. Kieffer, Ian Kitchen

Journal:

Year:

2010

Language:

english

File:

PDF, 540 KB

english, 2010

21

Recent advances in molecular recognition and signal transduction of active peptides: Receptors for opioid peptides

Brigitte L. Kieffer

Journal:

Cellular and Molecular Neurobiology

Year:

1995

Language:

english

File:

PDF, 1.58 MB

english, 1995

22

[35S]GTPγS binding: A tool to evaluate functional activity of a cloned opioid receptor transiently expressed in COS cells

Katia Befort, Lina Tabbara, Brigitte L. Kieffer

Journal:

Neurochemical Research

Year:

1996

Language:

english

File:

PDF, 707 KB

english, 1996

23

Effects of delta opioid receptors activation on a response inhibition task in rats

Katia Befort, Megan K. Mahoney, Carmen Chow, Scott J. Hayton, Brigitte L. Kieffer, Mary C. Olmstead

Journal:

Psychopharmacology

Year:

2011

Language:

english

File:

PDF, 412 KB

english, 2011

24

Murine inter-strain polymorphisms alter gene targeting frequencies at the mu opioid receptor locus in embryonic stem cells

Li Zhou, Daniel L. Rowley, Qing-Sheng Mi, Natasha Sefcovic, Hans W.D. Matthes, Brigitte L. Kieffer, David M. Donovan

Journal:

Mammalian Genome

Year:

2001

Language:

english

File:

PDF, 411 KB

english, 2001

25

Live molecular recognition: visualizing opioid receptors trafficking in vivo

Brigitte L. Kieffer

Journal:

Journal of Inclusion Phenomena and Macrocyclic Chemistry

Year:

2009

Language:

english

File:

PDF, 376 KB

english, 2009

26

Influence of Endogenous Opioid Systems on T Lymphocytes as Assessed by the Knockout of Mu, Delta and Kappa Opioid Receptors

Karaji, Ali G., Reiss, David, Matifas, Audrey, Kieffer, Brigitte L., Gavériaux-Ruff, Claire

Journal:

Journal of Neuroimmune Pharmacology

Year:

2011

Language:

english

File:

PDF, 390 KB

english, 2011

27

The delta agonists DPDPE and deltorphin II recruit predominantly mu receptors to produce thermal analgesia: a parallel study of mu, delta and combinatorial opioid receptor knockout mice

Grégory Scherrer, Katia Befort, Candice Contet, Jérôme Becker, Audrey Matifas, Brigitte L. Kieffer

Journal:

European Journal of Neuroscience

Year:

2004

Language:

english

File:

PDF, 405 KB

english, 2004

28

Identification of genes regulated in the mouse extended amygdala by excessive ethanol drinking associated with dependence

Candice Contet, Olivier Gardon, Dominique Filliol, Jérôme A. J. Becker, George F. Koob, Brigitte L. Kieffer

Journal:

Addiction Biology

Year:

2011

Language:

english

File:

PDF, 477 KB

english, 2011

29

Protracted abstinence from distinct drugs of abuse shows regulation of a common gene network

Julie Le Merrer, Katia Befort, Olivier Gardon, Dominique Filliol, Emmanuel Darcq, Doulaye Dembele, Jerome A. J. Becker, Brigitte L. Kieffer

Journal:

Addiction Biology

Year:

2012

Language:

english

File:

PDF, 1001 KB

english, 2012

30

Deletion of δ-opioid receptor in mice alters skin differentiation and delays wound healing

Mei Bigliardi-Qi, Claire Gaveriaux-Ruff, Hayan Zhou, Clarisse Hell, Pierre Bady, Theo Rufli, Brigitte Kieffer, Paul Lorenz Bigliardi

Journal:

Differentiation

Year:

2006

Language:

english

File:

PDF, 2.12 MB

english, 2006

31

The rewarding properties of MDMA are preserved in mice lacking µ-opioid receptors

Patricia Robledo, Victoria Mendizabal, Jordi Ortuño, Rafael De La Torre, Brigitte L. Kieffer, Rafael Maldonado

Journal:

European Journal of Neuroscience

Year:

2004

Language:

english

File:

PDF, 289 KB

english, 2004

32

Neuropathic pain is enhanced in δ-opioid receptor knockout mice

Xavier Nadal, Josep-Eladi Baños, Brigitte L. Kieffer, Rafael Maldonado

Journal:

European Journal of Neuroscience

Year:

2006

Language:

english

File:

PDF, 205 KB

english, 2006

33

Decreased motivation to eat in µ-opioid receptor-deficient mice

Francesco Papaleo, Brigitte L. Kieffer, Antoine Tabarin, Angelo Contarino

Journal:

European Journal of Neuroscience

Year:

2007

Language:

english

File:

PDF, 583 KB

english, 2007

34

Inflammatory pain is enhanced in delta opioid receptor-knockout mice

Claire Gavériaux-Ruff, Laurie A. Karchewski, Xavier Hever, Audrey Matifas, Brigitte L. Kieffer

Journal:

European Journal of Neuroscience

Year:

2008

Language:

english

File:

PDF, 576 KB

english, 2008

35

Identification of a novel family of G protein-coupled receptor associated sorting proteins

Frederic Simonin, Pascale Karcher, Julien J.-M. Boeuf, Audrey Matifas, Brigitte L. Kieffer

Journal:

Journal of Neurochemistry

Year:

2004

Language:

english

File:

PDF, 713 KB

english, 2004

36

Big dynorphin as a putative endogenous ligand for the κ-opioid receptor

Florence Merg, Dominique Filliol, Ivan Usynin, Igor Bazov, Niklas Bark, Yasmin L. Hurd, Tatjana Yakovleva, Brigitte L. Kieffer, Georgy Bakalkin

Journal:

Journal of Neurochemistry

Year:

2006

Language:

english

File:

PDF, 154 KB

english, 2006

37

Mu-opioid receptors are involved in the tolerance to nicotine antinociception

Lola Galeote, Brigitte L. Kieffer, Rafael Maldonado, Fernando Berrendero

Journal:

Journal of Neurochemistry

Year:

2006

Language:

english

File:

PDF, 205 KB

english, 2006

38

Mu-opioid receptors are involved in the tolerance to nicotine antinociception

Lola Galeote, Brigitte L. Kieffer, Rafael Maldonado, Fernando Berrendero

Journal:

Journal of Neurochemistry

Year:

2006

Language:

english

File:

PDF, 33 KB

english, 2006

39

Increased Ethanol Self-Administration in δ-Opioid Receptor Knockout Mice

Amanda J. Roberts, Lisa H. Gold, Ilham Polis, Jeffrey S. McDonald, Dominique Filliol, Brigitte L. Kieffer, George F. Koob

Journal:

Alcoholism: Clinical and Experimental Research

Year:

2001

Language:

english

File:

PDF, 149 KB

english, 2001

40

10.1038/76061

Kieffer, Brigitte L., Filliol, Dominique, Ghozland, Sandy, Chluba, Johanna, Martin, Miguel, Matthes, Hans W.D., Simonin, Frédéric, Befort, Katia, Gavériaux-Ruff, Claire, Dierich, Andrée, LeMeur, Maria

Journal:

Nature Genetics

Year:

2000

Language:

english

File:

PDF, 874 KB

english, 2000

41

Two faces for an opioid peptide—and more receptors for pain research

Simonin, Frédéric, Kieffer, Brigitte L.

Journal:

Nature Neuroscience

Year:

2002

Language:

english

File:

PDF, 84 KB

english, 2002

42

Opioid receptor random mutagenesis reveals a mechanism for G protein–coupled receptor activation

Décaillot, Fabien M, Befort, Katia, Filliol, Dominique, Yue, ShiYi, Walker, Philippe, Kieffer, Brigitte L

Journal:

Natural Structural Biology

Year:

2003

Language:

english

File:

PDF, 905 KB

english, 2003

43

The second extracellular loop: a damper for G protein–coupled receptors?

Massotte, Dominique, Kieffer, Brigitte L

Journal:

Nature Structural and Molecular Biology

Year:

2005

Language:

english

File:

PDF, 117 KB

english, 2005

44

Activity of mu- and delta-opioid agonists in vas deferens from mice deficient in MOR gene

Rafael Maldonado, Cintia Severini, Hans W D Matthes, Brigitte L Kieffer, Pietro Melchiorri, Lucia Negri

Journal:

British Journal of Pharmacology

Year:

2001

Language:

english

File:

PDF, 477 KB

english, 2001

45

Deletion of μ- and κ-Opioid Receptors in Mice Changes Epidermal Hypertrophy, Density of Peripheral Nerve Endings, and Itch Behavior

Bigliardi-Qi, Mei, Gaveriaux-Ruff, Claire, Pfaltz, Katrin, Bady, Pierre, Baumann, Tommy, Rufli, Theo, Kieffer, Brigitte L, Bigliardi, Paul L

Journal:

The Journal of Investigative Dermatology

Year:

2006

Language:

english

File:

PDF, 308 KB

english, 2006

46

Decreased Oral Self-Administration of Alcohol In κ-Opioid Receptor Knock-Out Mice

Krisztina M. Kovacs, Istvan Szakall, Danielle O’Brien, Ray Wang, K Yaragudri Vinod, Mariko Saito, Frederic Simonin, Brigitte L. Kieffer, Csaba Vadasz

Journal:

Alcoholism: Clinical and Experimental Research

Year:

2005

Language:

english

File:

PDF, 516 KB

english, 2005

47

Lack of dependence and rewarding effects of deltorphin II in mu-opioid receptor-deficient mice

Daniel M. Hutcheson, Hans W. D. Matthes, Emmanuel Valjent, Pilar Sánchez-Blázquez, Marta Rodríguez-Díaz, Javier Garzón, Brigitte L. Kieffer, Rafael Maldonado

Journal:

European Journal of Neuroscience

Year:

2001

Language:

english

File:

PDF, 184 KB

english, 2001

48

Preface

Donald W. Pfaff, Brigitte L. Kieffer

Journal:

Annals of the New York Academy of Sciences

Year:

2008

Language:

english

File:

PDF, 28 KB

english, 2008

49

Specific activation of the μ opioid receptor (MOR) by endomorphin 1 and endomorphin 2

Krisztina Monory, Marie-Claude Bourin, Mariana Spetea, Csaba Tömböly, Géza Tóth, Hans W. Matthes, Brigitte L. Kieffer, Jacques Hanoune, Anna Borsodi

Journal:

European Journal of Neuroscience

Year:

2000

Language:

english

File:

PDF, 269 KB

english, 2000

50

Influence of δ-Opioid Receptors in the Behavioral Effects of Nicotine

Berrendero, Fernando, Plaza-Zabala, Ainhoa, Galeote, Lola, Flores, África, Bura, S Andreea, Kieffer, Brigitte L, Maldonado, Rafael

Journal:

Neuropsychopharmacology

Year:

2012

Language:

english

File:

PDF, 646 KB

english, 2012